With the introduction of the new drug treatment for erectile dysfunction (ED) called Avanafil, many men who need some medication help in their love life wonder what are the advantages of Avanafil vs Sildenafil (Stendra vs Viagra). Patients are wondering whether the new treatment can successfully replace the well-established sildenafil treatment and provide some additional advantages. Both drugs belong to the same class of medications called phosphodiesterase type 5 inhibitors, or simply PDE5 inhibitors. These drugs block the effects of this enzyme, which is responsible for terminating the action of a biologically active chemical that causes an erection.

How do Avanafil and Sildenafil work and what are the differences?

When a man experiences sexual arousal, the brain sends signals to the nerve endings that are located in the penis in the cavernous bodies, through the release of nitric oxide (NO). This messenger activates an enzyme that produces high amounts of cGMP, which is the biologically active substance that directly dilates the blood vessels in the penis. This dilation of vessels allows for an increased entry of blood into the cavernous bodies, which results in an effective erection and a satisfactory sexual act. However, PDE5 is the enzyme that terminates the action of cGMP, which diminishes the erection in time. This mechanism may be more prominent in men who are unable to achieve effective erections. Both sildenafil and avanafil block the effects of PDE5, which greatly prolong the life of cGMP, which allows for a more potent and longer erection, leading to an improved sexual life in men suffering from ED. More cGMP obtained through the blocked enzyme PDE5 is what makes treatment of impotence or ED possible. Even though both drugs are similar in their mechanism of action, they have a major difference when it comes to their effects.

Viagra vs Avanafil

Avanafil is just as effective as sildenafil when employed in the treatment of ED and obtaining strong erections, but it has a substantially faster onset of action. For men who have a scheduled sexual activity and they know when a sexual intercourse is going to happen, sildenafil works just fine because they can plan when to take it to achieve the effects on time. Sildenafil starts working after 30 minutes up to an hour. Avanafil, on the other hand, starts working as soon as 15 minutes after ingestion, which makes it a great drug for people with unplanned sexual activity. Avanafil may have similar side effects with sildenafil, which are usually rare and temporary, and may include headaches, nausea, skin rash, digestive problems, among others. Consult with your doctor prior to taking avanafil or sildenafil for your ED problems.

John Rogers

I am working in Melbourne. My professional interests: male health and treatment ofyour sexual disorders.
John Rogers

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