Avanafil is a drug that is used primarily to treat erectile dysfunction (ED). It belongs to a medication class called phosphodiesterase type 5 inhibitors, also known as PDE5 inhibitor. It has been called “son of Viagra” because it belongs to the same category of drugs and has the same mechanism of action.

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*Avana is generic Avanafil tablet manufactured in India.

Mechanism of Action

Just like Viagra, Avanafil exerts its actions in the “Corpus cavernosum” of the penis, which is a small sponge-like structure that consists of multiple tiny chambers that are filled with blood during sexual arousal and result in an erection. When sexual stimulation occurs, Nitric Oxide (NO) is released, which stimulates a specific enzyme to produce more cGMP, a biologically active compound that causes blood vessel dilation, filling of corpus cavernosum with blood and erection. However, the action of cGMP is terminated by PDE5, which destroys cGMP thus ending its action. Avanafil inhibits PDE5 thus greatly prolonging the life of cGMP and causing a powerful erection in men suffering from erectile dysfunction.

Indication

Although ED is the main indication for Avanafil treatment, the drug is currently investigated as a potential treatment for pulmonary hypertension, because PDE5 enzyme is also present in the lungs.

Avanafil safety

Avanafil is a safe and effective treatment for ED. However, as with other medications, it has potential side effects, which are usually rare, temporary and mild. Side effects of avanafil may include headache, dizziness or digestive disturbances. No severe side effects that occurs with significant frequency has been observed. If you suffer from erectile dysfunction and your sexual life has been causing your trouble lately, there is no need to suffer in silence because Avanafil is designed to address your problems. Avanafil is FDA-approved for treatment of ED and successfully passed clinical trials and research studies with minimal side effects. Before considering treatment with Avanafil, please consult your doctor who will evaluate your health status and will adjust the dosage if necessary. Although Avanafil is very well tolerated by patients, make sure to inform your doctor of any unpleasant effects you may experience during treatment.